Recombinant Human TNFRSF11A Protein, His-tagged
Cat.No. : | TNFRSF11A-155H |
Product Overview : | Recombinant Human TNFRSF11A Protein with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | RANK (receptor activator of NF-κB) is a member of the tumor necrosis factor (TNF) receptor subfamily that is activated by its ligand, RANKL (TRANCE/OPGL/ODF), to promote survival of dendritic cells and differentiation of osteoclasts. Although RANK is widely expressed, its cell surface expression may be more restricted to dendritic cells and foreskin fibroblasts. RANK contains a 383-amino acid intracellular domain that associates with specific members of the TRAF family to NF-κB and JNK activiation. RANKL/RANK signaling may also lead to survival signaling through activation of the Akt pathway and an upregulation of survival proteins, including Bcl-xL. RANK signaling has been implicated as a potential therapeutic to inhibit bone loss and arthritis. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | ~21 kDa |
AA Sequence : | MIAPPCTSEKHYEHLGRCCNKCEPG KYMSSKCTTTSDSVCLPCGPDEYLD SWNEEDKCLLHKVCDTGKALVAVVA GNSTTPRRCACTAGYHWSQDCECCR RNTECAPGLGAQHPLQLNKDTVCKP CLAGYFSDAFSSTDKCRPWTNCTFL GKRVEHHGTEKSDAVCSSSLPARKP PNEPHVYLP |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator [ Homo sapiens (human) ] |
Official Symbol : | TNFRSF11A |
Synonyms : | TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, activator of NFKB; tumor necrosis factor receptor superfamily member 11A; CD265; RANK; receptor activator of NF-KB; osteoclast differentiation factor receptor; receptor activator of nuclear factor-kappa B; loss of heterozygosity, 18, chromosomal region 1; FEO; OFE; ODFR; OSTS; PDB2; OPTB7; TRANCER; LOH18CR1; |
Gene ID : | 8792 |
mRNA Refseq : | NM_003839 |
Protein Refseq : | NP_003830 |
MIM : | 603499 |
UniProt ID : | Q9Y6Q6 |
Products Types
◆ Recombinant Protein | ||
TNFRSF11A-184H | Recombinant Human TNFRSF11A Protein, His-tagged | +Inquiry |
Tnfrsf11a-112M | Recombinant Mouse Tnfrsf11a Protein, His (Fc)-Avi-tagged | +Inquiry |
Tnfrsf11a-185M | Recombinant Mouse Tnfrsf11a Protein, His-tagged | +Inquiry |
TNFRSF11A-235H | Recombinant Human TNFRSF11A Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF11A-9475M | Recombinant Mouse TNFRSF11A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF11A-1413RCL | Recombinant Rat TNFRSF11A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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