Recombinant Human TNFRSF1B Protein, His-tagged
Cat.No. : | TNFRSF1B-458H |
Product Overview : | Recombinant human TNFRSF1B protein with His tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized |
Molecular Mass : | 26 kDa |
Protein Length : | 461 |
AA Sequence : | MAPVAVWAALAVGLELWAAAHALPA QVAFTPYAPEPGSTCRLREYYDQTA QMCCSKCSPGQHAKVFCTKTSDTVC DSCEDSTYTQLWNWVPECLSCGSRC SSDQVETQACTREQNRICTCRPGWY CALSKQEGCRLCAPLRKCRPGFGVA RPGTETSDVVCKPCAPGTFSNTTSS TDICRPHQICNVVAIPGNASMDAVC TSTSPTRSMAPGAVHLPQPVSTRSQ HTQPTPEPSTAPSTSFLLPMGPSPP AEGSTGDFALPVGLIVGVTALGLLI IGVVNCVIMTQVKKKPLCLQREAKV PHLPADKARGTQGPEQQHLLITAPS SSSSSLESSASALDRRAPTRNQPQA PGVEASGAGEARASTGSSDSSPGGH GTQVNVTCIVNVCSSSDHSSQCSSQ ASSTMGDTDSSPSESPKDEQVPFSK EECAFRSQLETPETLLGSTEEKPLP LGVPDAGMKPS |
Purity : | > 98% |
Applications : | WB; ELISA; FACS; FC |
Stability : | This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : | At -20 centigrade. |
Concentration : | 1 mg/mL |
Storage Buffer : | PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : | Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
Gene Name : | TNFRSF1B tumor necrosis factor receptor superfamily, member 1B [ Homo sapiens (human) ] |
Official Symbol : | TNFRSF1B |
Synonyms : | TNFRSF1B; tumor necrosis factor receptor superfamily, member 1B; TNFR2; tumor necrosis factor receptor superfamily member 1B; CD120b; p75; TNF R II; TNF R75; TNFBR; TNFR80; TNF-R2; TNF-RII; p75 TNF receptor; p80 TNF-alpha receptor; soluble TNFR1B variant 1; tumor necrosis factor receptor 2; tumor necrosis factor beta receptor; tumor necrosis factor receptor type II; tumor necrosis factor binding protein 2; TBPII; TNFR1B; TNF-R75; p75TNFR; TNF-R-II; |
Gene ID : | 7133 |
mRNA Refseq : | NM_001066 |
Protein Refseq : | NP_001057 |
MIM : | 191191 |
UniProt ID : | P20333 |
Products Types
◆ Recombinant Protein | ||
TNFRSF1B-178H | Active Recombinant Human TNFRSF1B protein(Met1-Asp257), His&hFc-tagged | +Inquiry |
TNFRSF1B-01H | Active Recombinant Human TNFRSF1B Protein | +Inquiry |
Tnfrsf1b-448R | Recombinant Rat Tnfrsf1b Protein, His-tagged | +Inquiry |
TNFRSF1B-0765C | Recombinant Cynomolgus/Rhesus TNFRSF1B protein(Met1-Asp257), His-tagged | +Inquiry |
TNFRSF1B-5855R | Recombinant Rat TNFRSF1B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF1B-1048CCL | Recombinant Cynomolgus TNFRSF1B cell lysate | +Inquiry |
TNFRSF1B-2192MCL | Recombinant Mouse TNFRSF1B cell lysate | +Inquiry |
TNFRSF1B-851HCL | Recombinant Human TNFRSF1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket