Recombinant Human TNFRSF21
Cat.No. : | TNFRSF21-1604H |
- Specification
- Gene Information
- Related Products
Cat. No. : | TNFRSF21-1604H |
Description : | Death receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region; the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK. |
Molecular Weight : | The predicted molecular weight of Recombinant Human DR6 is Mr 60.3 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 65-75 kDa. |
Source : | Sf 21 Insect Cells. |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | TNFRSF21 tumor necrosis factor receptor superfamily, member 21 [ Homo sapiens ] |
Synonyms : | TNFRSF21; tumor necrosis factor receptor superfamily, member 21; DR6; BM-018; MGC31965; death receptor 6; death receptor 6; TNFR-related death receptor 6; OTTHUMP00000016561; OTTHUMP00000039915 |
Gene ID : | 27242 |
mRNA Refseq : | NM_014452 |
Protein Refseq : | NP_055267 |
MIM : | 605732 |
UniProt ID : | O75509 |
Chromosome Location : | p21 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | protein binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
Tnfrsf21-121M | Recombinant Mouse Tnfrsf21 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF21-363R | Recombinant Rat TNFRSF21 protein(Met1-His349), hFc-tagged | +Inquiry |
TNFRSF21-5856R | Recombinant Rat TNFRSF21 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tnfrsf21-3281M | Active Recombinant Mouse Tnfrsf21 protein(Met1-His349), His-tagged | +Inquiry |
TNFRSF21-687H | Active Recombinant Human TNFRSF21 protein(Met1-Leu350), hFc-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF21-2424MCL | Recombinant Mouse TNFRSF21 cell lysate | +Inquiry |
TNFRSF21-2977HCL | Recombinant Human TNFRSF21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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