Recombinant Human TNFRSF21, Fc-tagged
Cat.No. : | TNFRSF21-228H |
Product Overview : | The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351). |
- Specification
- Gene Information
- Related Products
Description : | DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the β-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6. |
Source : | HEK293 Cells |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized. Contains PBS. |
Molecular Mass : | ~80kDa (SDS-PAGE) |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Concentration : | 1mg/ml after reconstitution. |
Gene Name : | TNFRSF21 tumor necrosis factor receptor superfamily, member 21 [ Homo sapiens ] |
Official Symbol : | TNFRSF21 |
Synonyms : | TNFRSF21; tumor necrosis factor receptor superfamily, member 21; tumor necrosis factor receptor superfamily member 21; CD358; death receptor 6; DR6; TNFR-related death receptor 6; BM-018; MGC31965; |
Gene ID : | 27242 |
mRNA Refseq : | NM_014452 |
Protein Refseq : | NP_055267 |
MIM : | 605732 |
UniProt ID : | O75509 |
Chromosome Location : | 6p21.1 |
Pathway : | Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem; |
Function : | protein binding; receptor activity; |
Products Types
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Tnfrsf21-121M | Recombinant Mouse Tnfrsf21 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF21-206H | Recombinant Human TNFRSF21 Protein, Fc-tagged | +Inquiry |
Tnfrsf21-2033M | Recombinant Mouse Tnfrsf21 Protein, Fc/His-tagged | +Inquiry |
◆ Lysates | ||
TNFRSF21-2424MCL | Recombinant Mouse TNFRSF21 cell lysate | +Inquiry |
TNFRSF21-2977HCL | Recombinant Human TNFRSF21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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