Recombinant Human TNFRSF21 Protein, His-tagged

• Cat.No.: TNFRSF21-943H
• Product Overview: Recombinant Human TNFRSF21 fused with His tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
• Source: HEK293 cells
• Tag: His
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.4
• Molecular Mass: 34.62kD
• AA Sequence: QPEQKASNLIGTYRHVDRATGQVLT CDKCPAGTYVSEHCTNTSLRVCSSC PVGTFTRHENGIEKCHDCSQPCPWP MIEKLPCAALTDRECTCPPGMFQSN ATCAPHTVCPVGWGVRKKGTETEDV RCKQCARGTFSDVPSSVMKCKAYTD CLSQNLVVIKPGTKETDNVCGTLPS FSSSTSPSPGTAIFPRPEHMETHEV PSSTYVPKGMNSTESNSSASVRPKV LSSIQEGTVPDNTSSARGKEDVNKT LPNLQVVNHQQGPHHRHILKLLPSM EATGGEKSSTPIKGPKRGHPRQNLH KHFDINEHLVDHHHHHH
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: TNFRSF21 tumor necrosis factor receptor superfamily, member 21 [ Homo sapiens ]
• Official Symbol: TNFRSF21
• Synonyms: TNFRSF21; tumor necrosis factor receptor superfamily, member 21; tumor necrosis factor receptor superfamily member 21; CD358; death receptor 6; DR6; TNFR-related death receptor 6; BM-018; MGC31965
• Gene ID: 27242
• mRNA Refseq: NM_014452
• Protein Refseq: NP_055267
• MIM: 605732
• UniProt ID: O75509