Recombinant Human TNFRSF9 Protein, C-His-tagged
Cat.No. : | TNFRSF9-076H |
Product Overview : | Recombinant Human TNFRSF9 Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | TNFRSF9 is a member of the tumor necrosis factor receptor superfamily. It is also called 4-1BB or CD137. 4-1BB/CD137/TNFRSF9 is expressed in activated CD4+ and CD8+ T cells, natural killer cells and dendritic cells. The ligand 4-1BBL/CD137L/TNFSF9 on antigen presenting cells binds to 4-1BB/CD137/TNFRSF9 and costimulates the activation of T cells. The binding of agonistic antibodies to 4-1BB/CD137/TNFRSF9 also leads to costimulation for T cell activation. Studies have shown the effectiveness of targeting 4-1BB/CD137/TNFRSF9 by its agonistic antibodies in cancer immunotherapy. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~18 kDa |
AA Sequence : | LQDPCSNCPAGTFCDNNRNQICSPC PPNSFSSAGGQRTCDICRQCKGVFR TRKECSSTSNAECDCTPGFHCLGAG CSMCEQDCKQGQELTKKGCKDCCFG TFNDQKRGICRPWTNCSLDGKSVLV NGTKERDVVCGPSPADLSPGASSVT PPAPAREPGHSPQ |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | TNFRSF9 tumor necrosis factor receptor superfamily, member 9 [ Homo sapiens (human) ] |
Official Symbol : | TNFRSF9 |
Synonyms : | TNFRSF9; tumor necrosis factor receptor superfamily, member 9; ILA; tumor necrosis factor receptor superfamily member 9; 4 1BB; CD137; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor protein 4-1BB; T-cell antigen 4-1BB homolog; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; 4-1BB; CDw137; MGC2172; FLJ43501; |
Gene ID : | 3604 |
mRNA Refseq : | NM_001561 |
Protein Refseq : | NP_001552 |
MIM : | 602250 |
UniProt ID : | Q07011 |
Products Types
◆ Recombinant Protein | ||
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◆ Lysates | ||
TNFRSF9-2162HCL | Recombinant Human TNFRSF9 cell lysate | +Inquiry |
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TNFRSF9-1792MCL | Recombinant Mouse TNFRSF9 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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