Recombinant Human TNFSF9, His-tagged
Cat.No. : | TNFSF9-31579TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 71-254 of Human TNFSF9 with N-terminal His tag, 24kD. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Expressed in brain, placenta, lung, skeletal muscle and kidney. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRE GPELSPDDPA GLLDLRQGMF AQLVAQNVLL IDGPLSWYSD PGLAGVSLTGGLSYKEDTKE LVVAKAGVYY VFFQLELRRV VAGEGSGSVS LALHLQPLRS AAGAAALALT VDLPPASSEA RNSAFGFQGR LLHLSAGQRLGVHLHTEARA RHAWQLTQGA TVLGLFRVTP EIPAGLPSPR SE |
Sequence Similarities : | Belongs to the tumor necrosis factor family. |
Gene Name : | TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 [ Homo sapiens ] |
Official Symbol : | TNFSF9 |
Synonyms : | TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; 4 1BB L; homolog of mouse 4 1BB L; receptor 4 1BB ligand; |
Gene ID : | 8744 |
mRNA Refseq : | NM_003811 |
Protein Refseq : | NP_003802 |
MIM : | 606182 |
Uniprot ID : | P41273 |
Chromosome Location : | 19p13.3 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | cytokine activity; receptor binding; tumor necrosis factor receptor binding; |
Products Types
◆ Recombinant Protein | ||
TNFSF9-2019H | Recombinant Human TNFSF9 Protein, His-tagged | +Inquiry |
TNFSF9-1013R | Recombinant Rhesus TNFSF9 Protein (Arg128-Glu311), HlgG1 Fc-tagged | +Inquiry |
TNFSF9-231H | Active Recombinant Human TNFSF9 Protein (Leu 24 - Gln 186), His-tagged | +Inquiry |
Tnfsf9-324M | Recombinant Active Mouse TNFSF9 Protein, His-tagged(C-ter) | +Inquiry |
TNFSF9-585M | Recombinant Mouse TNFSF9 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
TNFSF9-1445RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
TNFSF9-2810MCL | Recombinant Mouse TNFSF9 cell lysate | +Inquiry |
TNFSF9-1444RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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