Recombinant Human TNIP3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TNIP3-2071H
• Product Overview: TNIP3 MS Standard C13 and N15-labeled recombinant protein (NP_001122315) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39 kDa
• AA Sequence: MAHFVQGTSRMIAAESSTEHKECAE PSTRKNLMNSLEQKIRCLEKQRKEL LEVNQQWDQQFRSMKELYERKVAEL KTKLDAAERFLSTREKDPHQRQRKD DRQREDDRHRDLTRDRLQREEKEKE RLNEELHELKEENKLLKGKNTLANK EKEHYECEIKRLNKALQDALNIKCS FSEDCLRKSRVEFCHEEMRTEMEVL KQQVQIYEEDFKKERSDRERLNQEK EELQQINETSQSQLNRLNSQIKACQ MEKEKLEKQLKQMYCPPCNCGLVFH LQDPWVPTGPGAVQKQREHPPDYQW YALDQLPPDVQHKANGLSSVKKVHP TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TNIP3 TNFAIP3 interacting protein 3 [ Homo sapiens (human) ]
• Official Symbol: TNIP3
• Synonyms: TNIP3; TNFAIP3 interacting protein 3; TNFAIP3-interacting protein 3; ABIN 3; FLJ21162; LIND; TNIP3 beta; ABIN-3 beta; Listeria induced; listeria-induced gene protein; TNFAIP3-interacting protein 3 beta; A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3
• Gene ID: 79931
• mRNA Refseq: NM_001128843
• Protein Refseq: NP_001122315
• MIM: 608019
• UniProt ID: Q96KP6