Recombinant Human TNNI3 Protein, His-Tagged
Cat.No. : | TNNI3-02H |
Product Overview : | Recombinant Human TNNI3 Protein, His-Tagged was expressed in E.coli cell. Recombinant Human TNNI3 protein produced in E.Coli is a full length protein containing a total of 260 amino acids and fused to a 6 His Tag at C-terminus, migrating as a 27kDa band on SDS-PAGE. Purified by proprietary chromatographic technique. |
- Specification
- Gene Information
- Related Products
Description : | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19. |
Source : | Escherichia coli |
Species : | Human |
Tag : | His |
Form : | Sterile Filtered clear solution. |
Molecular Mass : | 27kDa |
Protein Length : | 260 aa |
Purity : | Protein is >95% pure as determined by 12% PAGE (coomassie staining). |
Usage : | LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Stability : | TNNI3 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
Storage Buffer : | TNNI3 protein solution in PBS and 25mM arginine. |
Gene Name : | TNNI3 troponin I3, cardiac type [ Homo sapiens (human) ] |
Official Symbol : | TNNI3 |
Synonyms : | Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817. |
Gene ID : | 7137 |
mRNA Refseq : | NM_000363.5 |
Protein Refseq : | NP_000354.4 |
MIM : | 191044 |
UniProt ID : | P19429 |
Products Types
◆ Recombinant Protein | ||
Tnni3-6569M | Recombinant Mouse Tnni3 Protein, Myc/DDK-tagged | +Inquiry |
Tnni3-1003H | Active Recombinant Human cTnI Protein | +Inquiry |
TNNI3-2683H | Recombinant Human TNNI3 protein(11-130 aa), N-SUMO & N-His-tagged | +Inquiry |
TNNI3-871H | Recombinant Human TNNI3 Protein, His-tagged | +Inquiry |
TNNI3-9497M | Recombinant Mouse TNNI3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
TNNI3-01H | Native Human TNNI3 Protein | +Inquiry |
TNNI3-221H | Native Human TNNI3 | +Inquiry |
TNNI3-223H | Native Human Troponin I Type 3 (Cardiac) | +Inquiry |
◆ Lysates | ||
TNNI3-1803HCL | Recombinant Human TNNI3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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