Recombinant Human TPM3, MYC/DDK-tagged
Cat.No. : | TPM3-29H |
Product Overview : | Recombinant Human TPM3, transcript variant 2, fused with C-terminal MYC/DDK, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 cells |
Species : | Human |
Tag : | MYC/DDK |
Molecular Mass : | 28.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | TPM3 tropomyosin 3 [ Homo sapiens (human) ] |
Official Symbol : | TPM3 |
Synonyms : | TPM3; tropomyosin 3; NEM1; tropomyosin alpha-3 chain; TRK; tropomyosin-3; tropomyosin-5; gamma-tropomyosin; tropomyosin gamma; cytoskeletal tropomyosin TM30; heat-stable cytoskeletal protein 30 kDa; TM3; TM5; CFTD; TM-5; TM30; hTM5; TM30nm; TPMsk3; hscp30; OK/SW-cl.5; MGC3261; FLJ41118; MGC14582; MGC72094 |
Gene ID : | 7170 |
mRNA Refseq : | NM_153649 |
Protein Refseq : | NP_705935 |
MIM : | 191030 |
UniProt ID : | P06753 |
Chromosome Location : | 1q21.2 |
Pathway : | Adrenergic signaling in cardiomyocytes; Cardiac muscle contraction; Hypertrophic cardiomyopathy (HCM); Smooth Muscle Contraction |
Function : | actin binding; molecular_function |
Products Types
◆ Recombinant Protein | ||
TPM3-0146H | Recombinant Human TPM3 Protein (M2-I285), Tag Free | +Inquiry |
Tpm3-471R | Recombinant Rat Tpm3 Protein, His-tagged | +Inquiry |
TPM3-9538M | Recombinant Mouse TPM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPM3-5900R | Recombinant Rat TPM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tpm3-6600M | Recombinant Mouse Tpm3 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
TPM3-842HCL | Recombinant Human TPM3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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