Recombinant Human TRAF4 Protein (Gln193-Asp444), His tagged

• Cat.No.: TRAF4-6711H
• Product Overview: Recombinant human TRAF4 (Gln193-Asp444) fused with His tag was expressed in E. coli.

Specification

• Description: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 30.06 kDa
• Protein Length: Gln193-Asp444
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: TRAF4 TNF receptor-associated factor 4 [ Homo sapiens (human) ]
• Official Symbol: TRAF4
• Synonyms: TRAF4; TNF receptor-associated factor 4; CART1; MLN62; RNF83; MLN 62; malignant 62; RING finger protein 83; metastatic lymph node gene 62 protein; tumor necrosis receptor-associated factor 4A; cysteine-rich domain associated with ring and TRAF domain; cysteine-rich domain associated with RING and Traf domains protein 1
• Gene ID: 9618
• mRNA Refseq: NM_004295
• Protein Refseq: NP_004286
• MIM: 602464
• UniProt ID: Q9BUZ4