Recombinant Human TRIM8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TRIM8-594H
• Product Overview: TRIM8 MS Standard C13 and N15-labeled recombinant protein (NP_112174) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 61.5 kDa
• AA Sequence: MAENWKNCFEEELICPICLHVFVEP VQLPCKHNFCRGCIGEAWAKDSGLV RCPECNQAYNQKPGLEKNLKLTNIV EKFNALHVEKPPAALHCVFCRRGPP LPAQKVCLRCEAPCCQSHVQTHLQQ PSTARGHLLVEADDVRAWSCPQHNA YRLYHCEAEQVAVCQYCCYYSGAHQ GHSVCDVEIRRNEIRKMLMKQQDRL EEREQDIEDQLYKLESDKRLVEEKV NQLKEEVRLQYEKLHQLLDEDLRQT VEVLDKAQAKFCSENAAQALHLGER MQEAKKLLGSLQLLFDKTEDVSFMK NTKSVKILMDRTQTCTSSSLSPTKI GHLNSKLFLNEVAKKEKQLRKMLEG PFSTPVPFLQSVPLYPCGVSSSGAE KRKHSTAFPEASFLETSSGPVGGQY GAAGTASGEGQSGQPLGPCSSTQHL VALPGGAQPVHSSPVFPPSQYPNGS AAQQPMLPQYGGRKILVCSVDNCYC SSVANHGGHQPYPRSGHFPWTVPSQ EYSHPLPPTPSVPQSLPSLAVRDWL DASQQPGHQDFYRVYGQPSTKHYVT STRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TRIM8 tripartite motif containing 8 [ Homo sapiens (human) ]
• Official Symbol: TRIM8
• Synonyms: TRIM8; tripartite motif containing 8; ring finger protein 27, RNF27, tripartite motif containing 8; probable E3 ubiquitin-protein ligase TRIM8; GERP; glioblastoma expressed ring finger protein; ring finger protein 27; tripartite motif-containing 8; tripartite motif protein TRIM8; tripartite motif-containing protein 8; glioblastoma-expressed RING finger protein; RNF27
• Gene ID: 81603
• mRNA Refseq: NM_030912
• Protein Refseq: NP_112174
• MIM: 606125
• UniProt ID: Q9BZR9