Recombinant Human Tryptophan 2,3-Dioxygenase, T7-tagged
Cat.No. : | TDO2-823H |
Product Overview : | Recombinant TDO2 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 47872 Da. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TDO2-823H |
Description : | In Anopheles gambiae tryptophan 2,3-dioxygenase (TDO) is the only enzyme able to catalyze the first and ratelimiting step in L-Trp catabolism through the kynurenine pathway. On the contrary, in mammals, L-Trp can enter the kynurenine pathway through the alternative action of two enzymes, TDO and Indoleamine 2,3-dioxygenase (IDO). TDO converts L-tryptophan to N- formyl kynurenine by catalyzing the heme-dependent oxidative opening of the substrate indole ring. The metabolism of L-tryptophan (L-Trp) exceeding the protein synthesis requirements proceeds through several routes, generating a number of compounds that play multiple roles in controlling basic aspects of the biology of most living organisms. |
Sequences of amino acids : | 1-406 aa |
Formulation : | 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT. |
Purity : | 95% |
Gene Name : | TDO2 tryptophan 2,3-dioxygenase [ Homo sapiens ] |
Synonyms : | TDO; TPH2; TRPO; TDO2; tryptophan 2,3-dioxygenase; TO; tryptophanase; tryptophan oxygenase; tryptophan pyrrolase; tryptamin 2,3-dioxygenase;EC 1.13.11.11 |
Gene ID : | 6999 |
mRNA Refseq : | NM_005651 |
Protein Refseq : | NP_005642 |
MIM : | 191070 |
UniProt ID : | P48775 |
Chromosome Location : | 4q31-q32 |
Pathway : | Metabolic pathways; Tryptophan metabolism; Metabolism of amino acids and derivatives |
Function : | amino acid binding; heme binding; metal ion binding; oxidoreductase activity; oxygen binding; oxygen binding; tryptophan 2,3-dioxygenase activity |
Products Types
◆ Recombinant Protein | ||
TDO2-1536M | Recombinant Mouse TDO2 Protein (1-406 aa), His-tagged | +Inquiry |
Tdo2-6347M | Recombinant Mouse Tdo2 Protein, Myc/DDK-tagged | +Inquiry |
TDO2-4170H | Recombinant Human TDO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TDO2-1535H | Recombinant Human TDO2 Protein (1-406 aa), His-tagged | +Inquiry |
TDO2-1958R | Recombinant Rat TDO2 Protein (1-406 aa), His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
TDO2-1156HCL | Recombinant Human TDO2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket