Recombinant Human TYROBP Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | TYROBP-4167H |
Product Overview : | TYROBP MS Standard C13 and N15-labeled recombinant protein (NP_003323) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 12.2 kDa |
AA Sequence : | MGGLEPCSRLLLLPLLLAVSGLRPV QAQAQSDCSCSTVSPGVLAGIVMGD LVLTVLIALAVYFLGRLVPRGRGAA EAATRKQRITETESPYQELQGQRSD VYSDLNTQRPYYKTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | TYROBP TYRO protein tyrosine kinase binding protein [ Homo sapiens (human) ] |
Official Symbol : | TYROBP |
Synonyms : | TYROBP; TYRO protein tyrosine kinase binding protein; PLOSL; TYRO protein tyrosine kinase-binding protein; DAP12; DNAX activation protein 12; KARAP; killer activating receptor associated protein; PLO SL; KAR-associated protein; DNAX-activation protein 12; killer-activating receptor-associated protein; |
Gene ID : | 7305 |
mRNA Refseq : | NM_003332 |
Protein Refseq : | NP_003323 |
MIM : | 604142 |
UniProt ID : | O43914 |
Products Types
◆ Recombinant Protein | ||
TYROBP-6039R | Recombinant Rat TYROBP Protein, His (Fc)-Avi-tagged | +Inquiry |
TYROBP-9801M | Recombinant Mouse TYROBP Protein, His (Fc)-Avi-tagged | +Inquiry |
Tyrobp-6759M | Recombinant Mouse Tyrobp Protein, Myc/DDK-tagged | +Inquiry |
TYROBP-2287H | Recombinant Human TYROBP Protein, His (Fc)-Avi-tagged | +Inquiry |
TYROBP-519H | Recombinant Human TYROBP Protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
TYROBP-614HCL | Recombinant Human TYROBP 293 Cell Lysate | +Inquiry |
TYROBP-613HCL | Recombinant Human TYROBP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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