Recombinant Human UBA1 Protein, His-tagged

• Cat.No.: UBA1-337H
• Product Overview: Full length Recombinant Human UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1) Protein is produced in Insect Cells and is fused with a His tag at the N-terminal.

Specification

• Description: UBA1 (UniProt/Swiss-Prot entry P22314) is catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It activates ubiquitin by adenylating the C-terminal glycine residue with ATP and subsequently linking the adenylated glycine to the side chain of a cysteine residue in E1 thereby forming a ubiquitin-E1 thioester. UBA1 is also required for DNA repair response to replication stress.
• Source: Insect Cells
• Species: Human
• Tag: His
• Form: 20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
• Purity: Purified using FPLC, >95% purity as determined by SDS-PAGE.
• Notes: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
• Stability: Guaranteed stable for 2 years from date of receipt when stored properly.
• Storage: Store at -80 centigrade.
• Concentration: 0.5 µg/µl

Gene Information

• Gene Name: UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ]
• Official Symbol: UBA1
• Synonyms: UBA1; ubiquitin-like modifier activating enzyme 1; POC20; UBE1X; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; MGC4781
• Gene ID: 7317
• mRNA Refseq: NM_003334
• Protein Refseq: NP_003325
• MIM: 314370
• UniProt ID: P22314