Recombinant Human UBA3 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | UBA3-2793H |
Product Overview : | UBA3 MS Standard C13 and N15-labeled recombinant protein (NP_937838) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 49.9 kDa |
AA Sequence : | MADGEEPMAVDGGCGDTGDWEGRWN HVKKFLERSGPFTHPDFEPSTESLQ FLLDTCKVLVIGAGGLGCELLKNLA LSGFRQIHVIDMDTIDVSNLNRQFL FRPKDIGRPKAEVAAEFLNDRVPNC NVVPHFNKIQDFNDTFYRQFHIIVC GLDSIIARRWINGMLISLLNYEDGV LDPSSIVPLIDGGTEGFKGNARVIL PGMTACIECTLELYPPQVNFPMCTI ASMPRLPEHCIEYVRMLQWPKEQPF GEGVPLDGDDPEHIQWIFQKSLERA SQYNIRGVTYRLTQGVVKRIIPAVA STNAVIAAVCATEVFKIATSAYIPL NNYLVFNDVDGLYTYTFEAERKENC PACSQLPQNIQFSPSAKLQEVLDYL TNSASLQMKSPAITATLEGKNRTLY LQSVTSIEERTRPNLSKTLKELGLV DGQELAVADVTTPQTVLFKLHFTST RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | UBA3 ubiquitin-like modifier activating enzyme 3 [ Homo sapiens (human) ] |
Official Symbol : | UBA3 |
Synonyms : | UBA3; ubiquitin-like modifier activating enzyme 3; UBE1C, ubiquitin activating enzyme E1C (homologous to yeast UBA3), ubiquitin activating enzyme E1C (UBA3 homolog, yeast); NEDD8-activating enzyme E1 catalytic subunit; hUba3; ubiquitin activating enzyme E1 homolog (yeast); NEDD8-activating enzyme E1C; Nedd8-activating enzyme hUba3; ubiquitin-activating enzyme 3; ubiquitin-like modifier-activating enzyme 3; UBA3, ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1C (UBA3 homolog, yeast); ubiquitin-activating enzyme E1C (homologous to yeast UBA3); UBE1C; hUBA3; MGC22384; DKFZp566J164; |
Gene ID : | 9039 |
mRNA Refseq : | NM_198195 |
Protein Refseq : | NP_937838 |
MIM : | 603172 |
UniProt ID : | Q8TBC4 |
Products Types
◆ Recombinant Protein | ||
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Uba3-6766M | Recombinant Mouse Uba3 Protein, Myc/DDK-tagged | +Inquiry |
UBA3-522H | Recombinant Human UBA3 Protein, His-tagged | +Inquiry |
UBA3-4860R | Recombinant Rhesus Macaque UBA3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
UBA3-604HCL | Recombinant Human UBA3 293 Cell Lysate | +Inquiry |
UBA3-605HCL | Recombinant Human UBA3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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