Recombinant Human UBASH3B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UBASH3B-1864H
• Product Overview: UBASH3B MS Standard C13 and N15-labeled recombinant protein (NP_116262) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 72.7 kDa
• AA Sequence: MAQYGHPSPLGMAAREELYSKVTPR RNRQQRPGTIKHGSALDVLLSMGFP RARAQKALASTGGRSVQAACDWLFS HVGDPFLDDPLPREYVLYLRPTGPL AQKLSDFWQQSKQICGKNKAHNIFP HITLCQFFMCEDSKVDALGEALQTT VSRWKCKFSAPLPLELYTSSNFIGL FVKEDSAEVLKKFAADFAAEAASKT EVHVEPHKKQLHVTLAYHFQASHLP TLEKLAQNIDVKLGCDWVATIFSRD IRFANHETLQVIYPYTPQNDDELEL VPGDFIFMSPMEQTSTSEGWIYGTS LTTGCSGLLPENYITKADECSTWIF HGSYSILNTSSSNSLTFGDGVLERR PYEDQGLGETTPLTIICQPMQPLRV NSQPGPQKRCLFVCRHGERMDVVFG KYWLSQCFDAKGRYIRTNLNMPHSL PQRSGGFRDYEKDAPITVFGCMQAR LVGEALLESNTIIDHVYCSPSLRCV QTAHNILKGLQQENHLKIRVEPGLF EWTKWVAGSTLPAWIPPSELAAANL SVDTTYRPHIPISKLVVSESYDTYI SRSFQVTKEIISECKSKGNNILIVA HASSLEACTCQLQGLSPQNSKDFVQ MVRKIPYLGFCSCEELGETGIWQLT DPPILPLTHGPTGGFNWRETLLQET RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UBASH3B ubiquitin associated and SH3 domain containing B [ Homo sapiens (human) ]
• Official Symbol: UBASH3B
• Synonyms: UBASH3B; ubiquitin associated and SH3 domain containing B; ubiquitin-associated and SH3 domain-containing protein B; KIAA1959; SH3 domain containing 70 kDa protein; suppressor of T cell receptor signaling 1; nm23 phosphorylated unknown substrate; STS 1; T-cell ubiquitin ligand 2; cbl-interacting protein p70; Cbl-interacting protein Sts-1; nm23-phosphorylated unknown substrate; tyrosine-protein phosphatase STS1/TULA2; suppressor of T-cell receptor signaling 1; SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate; p70; STS1; STS-1; TULA-2; MGC15437
• Gene ID: 84959
• mRNA Refseq: NM_032873
• Protein Refseq: NP_116262
• MIM: 609201
• UniProt ID: Q8TF42