Recombinant Human UBE2D1 protein, GST-tagged
Cat.No. : | UBE2D1-005H |
Product Overview : | Recombinant Human UBE2D1 fused with GST tag at N-terminal was expressed in E.coli. |
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Description : | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | Lyophilized from a 0.2 µM filtered solution of 50mM HEPES,150mM NaCl,2mM DTT,10% Glycerin pH7.5 |
Molecular Mass : | 42.9kD |
AA Sequence : | MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPK LVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLVPRG SMALKRIQKELSDLQRDPPAHCSAG PVGDD |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | UBE2D1 ubiquitin conjugating enzyme E2 D1 [ Homo sapiens (human) ] |
Official Symbol : | UBE2D1 |
Synonyms : | SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1;UBE2D1; |
Gene ID : | 7321 |
mRNA Refseq : | NM_003338 |
Protein Refseq : | NP_003329 |
MIM : | 602961 |
UniProt ID : | P51668 |
Products Types
◆ Recombinant Protein | ||
UBE2D1-0040H | Recombinant Human UBE2D1 Protein (A2-M147), Tag Free | +Inquiry |
UBE2D1-9822M | Recombinant Mouse UBE2D1 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D1-6051R | Recombinant Rat UBE2D1 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D1-4868R | Recombinant Rhesus Macaque UBE2D1 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D1-0041H | Recombinant Human UBE2D1 Protein (A2-M147), His/Strep tagged | +Inquiry |
◆ Lysates | ||
UBE2D1-589HCL | Recombinant Human UBE2D1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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