Recombinant Human Ubiquitin Conjugating Enzyme 9, His6-Tagged
Cat.No. : | UBE2I-03H |
Product Overview : | Recombinant Human Ubiquitin Conjugating Enzyme 9 produced inE.coliis a single non-glycosylated polypeptide chain containing 171 amino acids and having a molecular mass of approximately 19.5 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | UBE2I -03H |
Description : | Human Ubquitin Conjugating Enzyme 9 (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumolyation, and may play a role in substrate recognition. Ubc9 can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, IκBα, and PML without the requirement of an E3 ligase. |
Purity : | >95% by SDS-PAGE and HPLC analyses. |
Formulation : | Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in 1×PBS, 1mM DTT, pH 7.5. |
Endotoxin : | Less than 1EU/μg of rHuUbc9 as determined by LAL method. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20oC. Further dilutions should be made in appropriate buffered solutions. |
Storage : | This lyophilized preparation is stable at 2-8oC, but should be kept at -20oC for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8oC. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20oC to -70oC. Avoid repeated freeze/thaw cycles. |
Gene Name : | UBE2I |
Synonyms : | P18; UBC9; C358B7.1; ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); UBC9_HUMAN; SUMO-conjugating enzyme UBC9; EC |
Gene ID : | 7329 |
mRNA Refseq : | NM_003345 |
Protein Refseq : | NP_003336 |
MIM : | 601661 |
UniProt ID : | P63279 |
Chromosome Location : | 16p13.3 |
Function : | HLH domain binding;ligase activity;protein binding; small conjugating protein ligase activity. |
Products Types
◆ Recombinant Protein | ||
UBE2I-4875R | Recombinant Rhesus Macaque UBE2I Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2I-856H | Recombinant Human UBE2I protein(Met1-Ser158) | +Inquiry |
Ube2i-6789M | Recombinant Mouse Ube2i Protein, Myc/DDK-tagged | +Inquiry |
UBE2I-0010H | Recombinant Human UBE2I Protein (S2-S158), His/Strep tagged | +Inquiry |
UBE2I-9830M | Recombinant Mouse UBE2I Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
UBE2I-574HCL | Recombinant Human UBE2I 293 Cell Lysate | +Inquiry |
UBE2I-573HCL | Recombinant Human UBE2I 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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