Recombinant Human UBQLN4 Protein, His-tagged

• Cat.No.: UBQLN4-528H
• Product Overview: Recombinant Human UBQLN4 Protein (Met1-Ser601) with N-His tag was expressed in E. coli.

Specification

• Description: Enables K48-linked polyubiquitin modification-dependent protein binding activity and identical protein binding activity. Involved in cellular response to DNA damage stimulus; negative regulation of double-strand break repair via homologous recombination; and regulation of cellular catabolic process. Located in several cellular components, including autophagosome; nucleoplasm; and site of DNA damage. Part of protein-containing complex. Colocalizes with cytosolic proteasome complex and nuclear proteasome complex.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 67.6 kDa
  Accurate Molecular Mass: 69 kDa
• Protein length: Met1-Ser601
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: UBQLN4 ubiquilin 4 [ Homo sapiens (human) ]
• Official Symbol: UBQLN4
• Synonyms: UBQLN4; ubiquilin 4; C1orf6, chromosome 1 open reading frame 6; ubiquilin-4; A1U; ataxin 1 ubiquitin like interacting protein; UBIN; connexin43-interacting protein of 75 kDa; ataxin-1 interacting ubiquitin-like protein; ataxin-1 ubiquitin-like interacting protein; ataxin-1 ubiquitin-like-interacting protein A1U; A1Up; CIP75; C1orf6
• Gene ID: 56893
• mRNA Refseq: NM_020131
• Protein Refseq: NP_064516
• MIM: 605440
• UniProt ID: Q9NRR5