Recombinant Human USP2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | USP2-886H |
Product Overview : | USP2 MS Standard C13 and N15-labeled recombinant protein (NP_741994) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 45.1 kDa |
AA Sequence : | MRTSYTVTLPEDPPAAPFPALAKEL RPRSPLSPSLLLSTFVGLLLNKAKN SKSAQGLAGLRNLGNTCFMNSILQC LSNTRELRDYCLQRLYMRDLHHGSN AHTALVEEFAKLIQTIWTSSPNDVV SPSEFKTQIQRYAPRFVGYNQQDAQ EFLRFLLDGLHNEVNRVTLRPKSNP ENLDHLPDDEKGRQMWRKYLEREDS RIGDLFVGQLKSSLTCTDCGYCSTV FDPFWDLSLPIAKRGYPEVTLMDCM RLFTKEDVLDGDEKPTCCRCRGRKR CIKKFSIQRFPKILVLHLKRFSESR IRTSKLTTFVNFPLRDLDLREFASE NTNHAVYNLYAVSNHSGTTMGGHYT AYCRSPGTGEWHTFNDSSVTPMSSS QVRTSDAYLLFYELASPPSRMTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | USP2 ubiquitin specific peptidase 2 [ Homo sapiens (human) ] |
Official Symbol : | USP2 |
Synonyms : | USP2; ubiquitin specific peptidase 2; ubiquitin specific protease 2; ubiquitin carboxyl-terminal hydrolase 2; UBP41; ubiquitin thioesterase 2; deubiquitinating enzyme 2; ubiquitin specific protease 9; ubiquitin specific protease 12; 41 kDa ubiquitin-specific protease; ubiquitin-specific-processing protease 2; USP9; |
Gene ID : | 9099 |
mRNA Refseq : | NM_171997 |
Protein Refseq : | NP_741994 |
MIM : | 604725 |
UniProt ID : | O75604 |
Products Types
◆ Recombinant Protein | ||
USP2-092H | Recombinant Human USP2 Protein, His-tagged | +Inquiry |
USP2-0550H | Recombinant Human USP2 Protein (N259-M605), His tagged | +Inquiry |
USP2-4937R | Recombinant Rhesus Macaque USP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP2-011H | Recombinant Human USP2 Protein, His-tagged | +Inquiry |
USP2-0551H | Recombinant Human USP2 Protein (N259-M605), Tag Free | +Inquiry |
◆ Lysates | ||
USP2-468HCL | Recombinant Human USP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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