Recombinant Human v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F, His-tagged

• Cat.No.: MAFF-550H
• Product Overview: MAFF, 1-164aa, Human His tag, E.coli

Specification

• Description: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. This protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. Recombinant human MAFF protein, fused to His-tag at N-terminus, was expressed in E.coli
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 20.1 kDa(187aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSVDPLS SKALKIKREL SENTPHLSDE ALMGLSVREL NRHLRGLSAE EVTRLKQRRR TLKNRGYAAS CRVKRVCQKE ELQKQKSELE REVDKLAREN AAMRLELDAL RGKCEALQGF ARSVAAARGP ATLVAPASVI TIVKSTPGSG SGPAHGPDPA HGPASCS
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MAFF v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) [ Homo sapiens ]
• Official Symbol: MAFF
• Synonyms: MAFF; v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian); v maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein F; transcription factor MafF; hMafF; v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F; U-MAF
• Gene ID: 23764
• mRNA Refseq: NM_001161572
• Protein Refseq: NP_001155044
• MIM: 604877
• UniProt ID: Q9ULX9
• Chromosome Location: 22q13.1
• Pathway: Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity