Recombinant Human Visinin-like 1
Cat.No. : | VSNL1-1406H |
Product Overview : | Recombinant human Visinin-like protein-1 was expressed inE.coliand purified by using conventional chromatography. MW =22.1 kDa (191aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | VSNL1-1406H |
Description : | Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. |
Source : | E.coli. |
Amino Acid Sequence : | MGKQNSKLAP EVMEDLVKST EFNEHELKQW YKGFLKDCPS GRLNLEEFQQ LYVKFFPYGD ASKFAQHAFR TFDKNGDGTI DFREFICALS ITSRGSFEQK LNWAFNMYDL DGDGKITRVE MLEIIEAIYK MVGTVIMMKM NEDGLTPEQR VDKIFSKMDK NKDDQITLDE FKEAAKSDPS IVLLLQCDIQ K |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol. |
Purity : | > 95 % by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | VSNL1 visinin-like 1 [ Homo sapiens ] |
Synonyms : | VSNL1; visinin-like 1; HLP3; VILIP; HPCAL3; HUVISL1; VILIP-1; OTTHUMP00000200482; OTTHUMP00000200483; hippocalcin-like protein 3; VLP-1; Hippocalcin-like protein 3; VISL1 |
Gene ID : | 7447 |
mRNA Refseq : | NM_003385 |
Protein Refseq : | NP_003376 |
MIM : | 600817 |
UniProt ID : | P62760 |
Chromosome Location : | 2p24.3 |
Function : | calcium ion binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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