Recombinant Human WDR43 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | WDR43-2101H |
Product Overview : | WDR43 MS Standard C13 and N15-labeled recombinant protein (NP_055946) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its targets genes. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 74.7 kDa |
AA Sequence : | MAAGGGGSCDPLAPAGVPCAFSPHS QAYFALASTDGHLRVWETANNRLHQ EYVPSAHLSGTCTCLAWAPARLQAK ESPQRKKRKSEAVGMSNQTDLLALG TAVGSILLYSTVKGELHSKLISGGH DNRVNCIQWHQDSGCLYSCSDDKHI VEWNVQTCKVKCKWKGDNSSVSSLC ISPDGKMLLSAGRTIKLWVLETKEV YRHFTGHATPVSSLMFTTIRPPNES QPFDGITGLYFLSGAVHDRLLNVWQ VRSENKEKSAVMSFTVTDEPVYIDL TLSENKEEPVKLAVVCRDGQVHLFE HILNGYCKKPLTSNCTIQIATPGKG KKSTPKPIPILAAGFCSDKMSLLLV YGSWFQPTIERVALNSREPHMCLVR DISNCWAPKVETAITKVRTPVMNSE AKVLVPGIPGHHAAIKPAPPQTEQV ESKRKSGGNEVSIEERLGAMDIDTH KKGKEDLQTNSFPVLLTQGLESNDF EMLNKVLQTRNVNLIKKTVLRMPLH TIIPLLQELTKRLQGHPNSAVLMVQ WLKCVLTVHASYLSTLPDLVPQLGT LYQLMESRVKTFQKLSHLHGKLILL ITQVTASEKTKGATSPGQKAKLVYE EESSEEESDDEIADKDSEDNWDEDE EESESEKDEDVEEEDEDAEGKDEEN GEDRDTASEKELNGDSDLDPENESE EETRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | WDR43 WD repeat domain 43 [ Homo sapiens (human) ] |
Official Symbol : | WDR43 |
Synonyms : | WDR43; WD repeat domain 43; UTP5; NET12; WD repeat-containing protein 43; U3 small nucleolar RNA-associated protein 5 homolog; UTP5, small subunit (SSU) processome component, homolog |
Gene ID : | 23160 |
mRNA Refseq : | NM_015131 |
Protein Refseq : | NP_055946 |
MIM : | 616195 |
UniProt ID : | Q15061 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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