Recombinant Human WWC2 Protein, His-tagged

• Cat.No.: WWC2-590H
• Product Overview: Recombinant Human WWC2 Protein (Thr960-Val1192) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 30.6 kDa
  Accurate Molecular Mass: 28 kDa
• Protein length: Thr960-Val1192
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: WWC2 WW and C2 domain containing 2 [ Homo sapiens (human) ]
• Official Symbol: WWC2
• Synonyms: WWC2; WW and C2 domain containing 2; BOMB; protein WWC2; BH3-only member B protein; WW, C2 and coiled-coil domain containing 2
• Gene ID: 80014
• mRNA Refseq: NM_024949
• Protein Refseq: NP_079225
• UniProt ID: Q6AWC2