Recombinant Human WWP2 Protein (A2-E870), His tagged
Cat.No. : | WWP2-0443H |
Product Overview : | Recombinant Human 6His-TEV-(GG)-WWP2(A2-E870 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Protein Length : | A2-E870 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 80% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 5% glycerol, 1 mM DTT. |
Shipping : | It is shipped out with blue ice. |
Gene Name : | WWP2 WW domain containing E3 ubiquitin protein ligase 2 [ Homo sapiens (human) ] |
Official Symbol : | WWP2 |
Synonyms : | WWP2; WW domain containing E3 ubiquitin protein ligase 2; NEDD4-like E3 ubiquitin-protein ligase WWP2; AIP2; WW domain-containing protein 2; atrophin-1 interacting protein 2; atrophin-1-interacting protein 2; Nedd-4-like ubiquitin-protein ligase; WWp2-like; |
Gene ID : | 11060 |
mRNA Refseq : | NM_007014 |
Protein Refseq : | NP_008945 |
MIM : | 602308 |
UniProt ID : | O00308 |
Products Types
◆ Recombinant Protein | ||
WWP2-5038R | Recombinant Rhesus Macaque WWP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
WWP2-376H | Recombinant Human WWP2 Protein, MYC/DDK-tagged | +Inquiry |
WWP2-0442H | Recombinant Human WWP2 Protein (A2-E870), Tag Free | +Inquiry |
Wwp2-7015M | Recombinant Mouse Wwp2 Protein, Myc/DDK-tagged | +Inquiry |
WWP2-5225R | Recombinant Rhesus monkey WWP2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
WWP2-001HCL | Recombinant Human WWP2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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