| Description : |
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
59.1 kDa |
| AA Sequence : |
MGDAPSPEEKLHLITRNLQEVLGEE KLKEILKERELKIYWGTATTGKPHV AYFVPMSKIADFLKAGCEVTILFAD LHAYLDNMKAPWELLELRVSYYENV IKAMLESIGVPLEKLKFIKGTDYQL SKEYTLDVYRLSSVVTQHDSKKAGA EVVKQVEHPLLSGLLYPGLQALDEE YLKVDAQFGGIDQRKIFTFAEKYLP ALGYSKRVHLMNPMVPGLTGSKMSS SEEESKIDLLDRKEDVKKKLKKAFC EPGNVENNGVLSFIKHVLFPLKSEF VILRDEKWGGNKTYTAYVDLEKDFA AEVVHPGDLKNSVEVALNKLLDPIR EKFNTPALKKLASAAYPDPSKQKPM AKGPAKNSEPEEVIPSRLDIRVGKI ITVEKHPDADSLYVEKIDVGEAEPR TVVSGLVQFVPKEELQDRLVVVLCN LKPQKMRGVESQGMLLCASIEGINR QVEPLDPPAGSAPGEHVFVKGYEKG QPDEELKPKKKVFEKLQADFKISEE CIAQWKQTNFMTKLGSISCKSLKGG NISTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
