Recombinant Mouse Abca8b protein, His & T7-tagged

• Cat.No.: Abca8b-8142M
• Product Overview: Recombinant Mouse Abca8b aa. (Ala1303~Glu1514 (Accession # Q8K440)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.7kDa.
• Protein length: Ala1303~Glu1514 (Accession # Q8K440)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: Abca8b ATP-binding cassette, sub-family A (ABC1), member 8b [ Mus musculus (house mouse) ]
• Official Symbol: Abca8b
• Synonyms: Abca8b; ATP-binding cassette, sub-family A (ABC1), member 8b; Abca8; ATP-binding cassette sub-family A member 8-B
• Gene ID: 27404
• mRNA Refseq: NM_013851.2
• Protein Refseq: NP_038879.2
• UniProt ID: Q8K440

Reviews

08/23/2018

The customer service responded quickly and solved my problem in time.

08/10/2018

a trustworthy company.

05/19/2018

Express delivery is fast. Accelerated my research progress.

Q&As

Can you achieve 95% purity?

Yes. You can also customize product purity.

Why can't I find any more information on this protein?

Scientists are working hard to advance the research progress of this protein, and we believe that we will know the whole picture of this protein in the near future.

Are there any protein products of ABCA8b obtained from other expression systems?

Our recombinant protein products can be customized according to customer needs, you can contact our experts to inform the needs.

Is there a discount for buying this product now?

10% off on all products and 5% off on all services during Nov. 14, 2022 – Jan. 6, 2023

How should I store this product after receiving it?

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Will CSPG4 interact with ABCA8b?

Chondroitin sulfate proteoglycan 4 interacts with ABCA8.

Why do Abca8b -/- mice exhibit slower cerebellar signal conduction velocity in compound action potentials experiments?

Decreased cerebellar myelination and the disordered myelin sheath ultrastructure in Abca8b -/- mice result in decreased cerebellar fiber conduction velocity.

How to determine whether abca8b is expressed in the brain?

Abca8b expression can be determined by tissue expression analyses, in situ hybridization or quantitative PCR.

What is the major function of ABCA8B?

ABCA8b is responsible for mediating cholesterol and taurocholate efflux. Regulates HDL cholesterol levels by enhancing cholesterol efflux to lipid-free APOA1 through interaction with ABCA1.