Recombinant Mouse AGTR1B Protein, His (Fc)-Avi-tagged

• Cat.No.: AGTR1B-398M
• Product Overview: Recombinant Mouse AGTR1B with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Mouse
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Agtr1b angiotensin II receptor, type 1b [ Mus musculus ]
• Official Symbol: AGTR1B
• Gene ID: 11608
• mRNA Refseq: NM_175086.3
• Protein Refseq: NP_780295.2
• UniProt ID: P29755

Reviews

09/17/2021

Very satisfied with the product.

08/18/2020

These recombinant proteins are a steal—affordable, reliable, and perfect for my research!

07/22/2019

The ordering process was smooth, and the recombinant proteins arrived on time and intact

05/11/2019

The friendly support team went above and beyond to assist me in choosing the right proteins

02/02/2019

Highly pure recombinant proteins that consistently delivered excellent results—definitely recommend

Q&As

Does AGTR1B have a role in stress response?

AGTR1B activation is involved in the hypothalamic-pituitary-adrenal (HPA) axis response to stress, influencing the release of stress-related hormones.

Can AGTR1B influence mood and behavior?

AGTR1B in the brain has been associated with mood regulation and behavioral responses, and alterations in AGTR1B signaling have been implicated in psychiatric disorders.

How is AGTR1B involved in neurological processes?

AGTR1B in the brain plays a role in regulating neurotransmitter release, neuroinflammation, neuronal survival, and synaptic plasticity, potentially impacting neurological disorders.

How is AGTR1B involved in blood pressure regulation?

AGTR1B activation in the brain influences sympathetic outflow, vasopressin release, and renal function, contributing to the regulation of blood pressure.

What signaling pathways are activated by AGTR1B?

AGTR1B activation leads to the activation of intracellular signaling pathways, including phospholipase C (PLC), protein kinase C (PKC), and mitogen-activated protein kinases (MAPKs).

How can AGTR1B activity be measured in the laboratory?

AGTR1B activity can be measured through functional assays, such as calcium mobilization assays or cAMP.

How does AGTR1B influence cardiovascular remodeling?

AGTR1B activation in the heart and blood vessels can contribute to cardiac hypertrophy, fibrosis, and vascular remodeling, which are associated with cardiovascular diseases.

Can AGTR1B activation contribute to inflammation?

AGTR1B activation in immune cells and the brain can modulate inflammatory processes, potentially impacting inflammatory diseases.

How is AGTR1B involved in the regulation of body fluid balance?

AGTR1B activation in specific brain regions modulates water intake, renal function, and the secretion of antidiuretic hormone (ADH) to regulate body fluid balance.

Can AGTR1B affect cellular growth and proliferation?

Activation of AGTR1B by angiotensin II can promote cell growth, proliferation, and hypertrophy in various tissues, contributing to tissue remodeling and pathological processes.