Recombinant Mouse AKR1B7 Protein

• Cat.No.: AKR1B7-1493M
• Product Overview: Recombinant Mouse AKR1B7 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Akr1b7 aldo-keto reductase family 1, member B7 [ Mus musculus ]
• Official Symbol: AKR1B7
• Gene ID: 11997
• mRNA Refseq: NM_009731.2
• Protein Refseq: NP_033861.2
• UniProt ID: P21300

Reviews

10/10/2022

The functional activity of AKR1B7 was verified by several methods, and the results were consistent and reliable.

09/27/2022

The quality of AKR1B7 was stable and reliable, and there was no significant difference between different batches.

08/26/2022

Good solubility and is easy to manipulate and purify.

07/21/2021

AKR1B7 has a wide range of applications in scientific research and is suitable for a variety of experimental designs and research purposes.

Q&As

Whether AKR1B7 protein influences diabetes progression?

AKR1B7 protein is closely related to the occurrence and development of diabetes mellitus and is involved in a variety of enzyme reactions in the glucose metabolism pathway, especially the regulation of glucose-ketose isomerase and aldose reductase.

What role does AKR1B7 protein play in the regulation of blood sugar levels?

AKR1B7 protein is involved in the metabolism of polysaccharide and mannose, and has a certain regulation effect on blood glucose level.

In what diseases do AKR1B7 inhibitors have potential applications?

The development of AKR1B7 inhibitors may be expected to be an effective treatment for cancer treatment and metabolic diseases such as diabetes.

Is AKR1B7 protein involved in cancer occurrence and development?

AKR1B7 protein may have a certain relationship with the occurrence and development of cancer, especially pancreatic, breast, colorectal, lung and other cancers.

Where does AKR1B7 exist in the body and how does it work?

AKR1B7 protein is involved in the metabolism of polysaccharides and other substances, and may also have antioxidant and neuroprotective effects.

What is the role of AKR1B7 protein in the cardiac system?

AKR1B7 protein is involved in the occurrence and development of cardiovascular disease in multiple aspects including vascular function, oxidative stress and inflammation.

Is AKR1B7 protein associated with tumor immune microenvironment?

Current studies suggest that AKR1B7 protein is involved in the regulation of autophagy, metabolic reprogramming and tumor microenvironment in some tumor cells, thus participating in tumor proliferation and metastasis.

Whether AKR1B7 protein has an improving effect on neurodegenerative diseases?

AKR1B7 protein can be involved in the treatment and prevention of neurodegenerative diseases by inhibiting ROS production, anti-neuronal apoptosis, inhibiting NF-κB and other mechanisms.

Does AKR1B7 protein contribute to nonalcoholic fatty liver disease?

AKR1B7 protein can promote the dehydrogenase reaction of fatty acids, increase liver fatty acid synthesis, and lead to the occurrence and development of nonalcoholic fatty liver disease.

Whether AKR1B7 protein is present in the human body?

AKR1B7 protein is an aldose reductase, which is mainly involved in the metabolic process of polysaccharides, polyphenols, steroids, etc.

What diseases is AKR1B7 associated with?

AKR1B7 protein has been associated with metabolic diseases such as diabetes, non-alcoholic fatty liver disease, neurodegenerative diseases, tumors, etc.

How does AKR1B7 affect liver function?

AKR1B7 protein may be involved in processes such as oxidative stress and inflammation in the liver, thereby affecting liver metabolism and function.

Which cell signaling pathways does AKR1B7 protein participate in?

AKR1B7 protein is involved in a variety of cellular signaling pathways, such as NF-κB, MAPK, PI3K/Akt and other signaling pathways.

What diseases are AKR1B7 mutations and polymorphisms associated with?

AKR1B7 mutation and polymorphism are related to the occurrence and development of metabolic diseases such as diabetes and a variety of cancers.

What are the methods for laboratory detection of AKR1B7 protein?

AKR1B7 protein is mainly detected in laboratory by Western blotting and enzyme-linked immunosorbent assay.