Recombinant Mouse ALMS1 Protein, His (Fc)-Avi-tagged

• Cat.No.: ALMS1-480M
• Product Overview: Recombinant Mouse ALMS1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Mouse
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Alms1 Alstrom syndrome 1 [ Mus musculus ]
• Official Symbol: ALMS1
• Gene ID: 236266
• mRNA Refseq: NM_145223.2
• Protein Refseq: NP_660258.2
• UniProt ID: Q8K4E0

Reviews

07/24/2022

Good stability under different temperature and humidity conditions.

06/19/2022

The effect of chemical modification, such as PEGylation or glycosylation, is small.

03/27/2020

Accurate localization and function in cells.

07/24/2019

ALMS1 was effective in removing impurities during purification.

Q&As

In which tissues and organs is ALMS1 gene expressed?

The ALMS1 gene is expressed in several tissues and organs, including the retina, cerebral cortex, small intestine, kidney, and pancreas.

How is Alstrom syndrome inherited?

Alstrom syndrome is an autosomal recessive disorder caused by a mutation in the ALMS1 gene.

Which cancers are linked to mutations in the ALMS1 gene?

No studies have shown that ALMS1 mutations are associated with cancer.

How does ALMS1 mutation affect protein function?

Mutations in the ALMS1 gene may lead to changes in the structure or function of the ALMS1 protein, which may affect its role in the cell as well as the metabolism and signaling processes of the entire cell.

What are the symptoms of Alstrom syndrome that are currently treated?

There are treatments that address the symptoms of Alstrom syndrome, including vision rehabilitation training, diabetes treatment, and hearing tests.

What does the ALMS1 gene code for?

The ALMS1 gene encodes the ALMS1 protein, the function of which is not fully understood.

Is there any research on the role of ALMS1 gene in nervous system development?

Yes, some research suggests that the ALMS1 gene may also have a role in nervous system development.

Are ALMS1 mutations diverse?

Yes, there is a great diversity of ALMS1 mutations.

Is ALMS1 gene mutation associated with congenital heart disease?

There are few studies on the relationship between ALMS1 gene mutation and congenital heart disease, and there is no clear conclusion at present.

Are there any studies showing that ALMS1 gene mutations are associated with diseases related to the immune system?

Some studies suggest that ALMS1 gene mutations may be associated with autoimmune diseases, rheumatoid arthritis, etc.

Does the ALMS1 gene mutation affect people's intelligence?

Mutations in the ALMS1 gene may affect intellectual development, but the extent of the effect is less certain.

Is there a gene therapy method for ALMS1 gene mutation?

There is currently no gene therapy for the ALMS1 gene mutation.

What symptoms and diseases do mutations in the ALMS1 gene cause?

Mutations in the ALMS1 gene can cause Alstrom syndrome, which has symptoms including early blindness, obesity, diabetes, deafness and more.

Can the ALMS1 gene mutation be passed on to the next generation?

Yes, because Alstrom syndrome is an autosomal recessive disorder, the ALMS1 gene mutation may be passed on to the next generation.