Recombinant Mouse AMD2 Protein

• Cat.No.: AMD2-1592M
• Product Overview: Recombinant Mouse AMD2 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Amd2 S-adenosylmethionine decarboxylase 2 [ Mus musculus ]
• Official Symbol: AMD2
• Gene ID: 100041585
• mRNA Refseq: NM_007444.3
• Protein Refseq: NP_031470.3
• UniProt ID: D3Z6H8

Reviews

06/18/2022

High-throughput compatibility for efficient data acquisition.

08/04/2021

Reduced assay optimization time for faster results.

05/20/2020

Stable reagents for long-term assay reproducibility.

Q&As

What is the subcellular localization of AMD2 and how does it impact its function?

AMD2 is primarily localized in the mitochondria, where it functions in specific metabolic pathways.

What are the molecular interactions of AMD2 with other proteins and their functional implications?

AMD2 interacts with other proteins involved in mitochondrial metabolism and redox regulation, modulating cellular processes such as energy production and antioxidant defense.

Can AMD2 deficiency or overexpression lead to cellular dysfunction or disease phenotypes?

Alterations in AMD2 expression, deficiency, or dysregulation may lead to mitochondrial dysfunction, impaired metabolism, and contribute to disease phenotypes, such as neurodegenerative disorders or metabolic disorders.

What are the downstream signaling pathways or cellular processes regulated by AMD2 activity?

AMD2 activity can impact downstream signaling pathways, including those involved in cellular adaptation to oxidative stress and metabolic homeostasis.

How does AMD2 affect cellular metabolism and energy production?

AMD2 is involved in cellular metabolism by participating in energy production through mitochondrial respiration and the generation of ATP.

How does AMD2 contribute to cellular redox balance and oxidative stress response?

AMD2 plays a role in maintaining cellular redox balance by participating in mitochondrial redox reactions and antioxidant systems.

What is the enzymatic activity of AMD2 and its role in specific metabolic pathways?

AMD2 possesses enzymatic activity, such as dehydrogenase or oxidoreductase activity, and contributes to specific metabolic pathways, including the tricarboxylic acid cycle and oxidative phosphorylation.

What are the structural features of AMD2 that are critical for its enzymatic activity and substrate specificity?

The enzymatic activity and substrate specificity of AMD2 are determined by its unique protein structure, including active site residues and cofactor binding sites.

How is AMD2 expression regulated during cellular development and in response to environmental stimuli?

AMD2 expression is regulated at transcriptional and post-transcriptional levels, influenced by developmental cues and environmental factors.

How does AMD2 expression or activity correlate with disease states, and can it serve as a therapeutic target?

Dysregulation of AMD2 expression or activity has been implicated in various diseases, including neurodegenerative diseases and metabolic disorders, highlighting its potential as a therapeutic target for intervention and treatment strategies.