| Description : |
Enables ubiquitin protein ligase binding activity. Involved in several processes, including double-strand break repair; positive regulation of DNA repair; and smooth muscle contraction. Acts upstream of or within several processes, including generation of neurons; negative regulation of neuron differentiation; and visual learning. Located in cytoplasm and nucleus. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and neuromuscular junction. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human APBB1 (amyloid beta precursor protein binding family B member 1). |
| Source : |
E. coli |
| Species : |
Mouse |
| Tag : |
N-His |
| Form : |
Freeze-dried powder |
| Molecular Mass : |
Predicted Molecular Mass: 29.2 kDa
Accurate Molecular Mass: 40 kDa |
| Protein length : |
Pro182-Met412 |
| Purity : |
> 90% |
| Applications : |
Positive Control; Immunogen; SDS-PAGE; WB. |
| Stability : |
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
| Storage Buffer : |
PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300. |
| Reconstitution : |
Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
