Recombinant Mouse APH1C Protein

• Cat.No.: APH1C-1769M
• Product Overview: Recombinant Mouse APH1C full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Aph1c anterior pharynx defective 1c homolog (C. elegans) [ Mus musculus ]
• Official Symbol: APH1C
• Gene ID: 68318
• mRNA Refseq: NM_026674.3
• Protein Refseq: NP_080950.1
• UniProt ID: Q9DCZ9

Reviews

11/07/2021

Low carbon emissions and friendly to the environment.

05/30/2021

The short half-life and high clearance characteristics of APH1C give it greater advantages in tissue penetration and better access to the lesion site.

08/16/2019

Stability of APH1C is very good, and its performance remains unchanged after repeated use, which brings great convenience to our experiment.

07/12/2019

Specificity in Western blot is very good, the binding ability to the target protein is strong, and the cross-reactivity is low, indicating that it has high specificity and low cross-reactivity.

Q&As

Can APH1C be used for early diagnosis of Alzheimer's disease?

APH1C could be used as a biomarker for early diagnosis of Alzheimer's disease.

How does APH1C play a role in neurodegenerative diseases?

APH1C is involved in the regulation of Notch signaling pathway in neurodegenerative diseases, thus affecting physiological functions of the nervous system.

What is the application of APH1C in the screening of compound drugs?

APH1C is involved in Notch signaling pathway and can be used as a target for screening compound drugs.

What type of protein is APH1C?

APH1C is a transmembrane protein.

Does APH1C have the potential to treat cancer?

APH1C plays an important role in the regulation of tumor growth and metastasis, and therefore has the potential to treat cancer.

APH1C expression is related to which sex, age and race?

The expression of APH1C is related to gender, age, race and other factors.

What is the location of APH1C in mammalian cells?

APH1C is mainly located in the endoplasmic reticulum and Golgi apparatus.

What is the role of APH1C in apoptosis?

APH1C is involved in the regulation of apoptosis.

Which diseases is APH1C related to?

APH1C is mainly associated with neurodegenerative diseases, tumors and other diseases, such as Alzheimer's disease, cancer, etc.

Is APH1C gene susceptible to mutation?

The gene for the APH1C has been associated with susceptibility to Alzheimer's disease, and the susceptibility mutations need to be further studied.

Which signaling pathways are involved in APH1C ?

APH1C is involved in Notch signaling pathway.

How to evaluate the biological activity of APH1C ?

The biological activity of APH1C can be evaluated by cell culture experiment and mouse model experiment.

How to detect post-translational modification of APH1C ?

Post-translational modifications of APH1C s can be detected by mass spectrometry and other methods.

How to detect the expression level of APH1C ?

The expression level of APH1C could be detected by Western blot, immunohistochemistry and other methods.

What role does APH1C play in cell growth and differentiation?

APH1C plays a key role in cell growth and differentiation.

In what aspects of cancer treatment does APH1C have clinical application prospects?

PH1C can be used to design brain agonists as targets for anticancer drugs.

How does APH1C interact with other proteins?

APH1C s interact with a variety of proteins, such as nicastrin, pen-2, etc.

In what drug research is APH1C widely used?

APH1C is widely used in anticancer drug research and neurological disease drug research.