Recombinant Mouse ART2B Protein Pre-coupled Magnetic Beads

• Cat.No.: ART2B-763M-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Mouse
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Art2b ADP-ribosyltransferase 2b [ Mus musculus ]
• Official Symbol: ART2B
• Gene ID: 11872
• mRNA Refseq: NM_019915.2
• Protein Refseq: NP_064299.2
• UniProt ID: O35975

Reviews

11/01/2020

Its impeccable purity and consistency have consistently delivered accurate and robust results, enabling me to make significant strides in my research.

08/29/2017

I confidently recommend the ART2B protein to any researcher seeking a superior protein that not only fulfills their experimental needs but is also backed by unparalleled support from the manufacturer.

07/28/2017

The Aldehyde Protein exhibits an exceptional level of quality that surpasses my experimental requirements.

Q&As

Are there any known diseases or disorders associated with mutations in the ART2B gene?

Mutations in the ART2B gene have not been directly linked to specific diseases or disorders in humans so far.

What are some known substrates of ART2B?

ART2B ADP-ribosylates specific arginine residues on target proteins, including P2X purinergic receptors and certain immune cell markers.

Is the activity of ART2B influenced by any cofactors or regulators?

ART2B activity is dependent on the presence of NAD+ as a substrate and can also be influenced by extracellular ATP levels and calcium concentrations.

Are there any therapeutic applications targeting ART2B?

Currently, there are no specific therapeutics targeting ART2B for direct modulation. However, research on ADP-ribosylation and its associated pathways may have therapeutic implications in the future.

Does ART2B have any non-enzymatic functions or interactions with other proteins?

Apart from its enzymatic role in ADP-ribosylation, ART2B does not have any known non-enzymatic functions or specific protein interactions.

Does ART2B activity change under pathological conditions?

The dysregulation of ADP-ribosylation, including ART2B activity, has been implicated in various diseases. However, the specific role of ART2B in these conditions requires further investigation.

How does ART2B catalyze ADP-ribosylation?

ART2B transfers ADP-ribose from NAD+ to specific target proteins, modifying their structure and function.