Recombinant Mouse ART3 Protein Pre-coupled Magnetic Beads

• Cat.No.: ART3-764M-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Mouse
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Art3 ADP-ribosyltransferase 3 [ Mus musculus ]
• Official Symbol: ART3
• Gene ID: 109979
• mRNA Refseq: NM_181728.2
• Protein Refseq: NP_859417.2
• UniProt ID: Q8R2G4

Reviews

01/02/2023

The ART3 Protein boasts remarkable stability, ensuring its integrity is maintained during storage and experimentation.

08/18/2022

One remarkable aspect of the ART3 Protein is the outstanding technical support provided by the manufacturer.

06/29/2016

Equally noteworthy is the remarkable technical support provided by the manufacturer.

Q&As

What are some known substrates of ART3?

ART3 ADP-ribosylates specific arginine residues on target proteins, including CD28, a critical co-stimulatory molecule in T cell activation.

Are there any known diseases or disorders associated with mutations in the ART3 gene?

Mutations in the ART3 gene have not been directly linked to specific diseases or disorders in humans so far.

How is ART3 expression regulated in normal physiological conditions?

The precise regulation of ART3 gene expression is not well characterized, but it may be influenced by various cellular and immune signaling pathways.

Is the activity of ART3 influenced by any cofactors or regulators?

ART3 activity depends on the availability of NAD+ as a substrate and can also be influenced by various cellular signaling pathways related to immune responses.

Does ART3 activity change under pathological conditions?

Dysregulated ADP-ribosylation, including ART3 activity, has been implicated in various diseases. However, the specific role of ART3 in these conditions requires further investigation.

Are there any known animal models or experimental systems used to study ART3 functions?

Animal models, such as ART3 knockout mice, have been generated to investigate the role of ART3 in vivo, providing insights into its physiological functions.

How does ART3 catalyze ADP-ribosylation?

ART3 transfers ADP-ribose from NAD+ to specific target proteins, modifying their structure and function.