Recombinant Mouse Ass1 protein, His&Myc-tagged

• Cat.No.: Ass1-391M
• Product Overview: Recombinant Mouse Ass1 protein(P16460)(1-412aa), fused with N-terminal His tag and C-terminal Myc tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His&Myc
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 51.6 kDa
• Protein length: 1-412aa
• AA Sequence: MSSKGSVVLAYSGGLDTSCILVWLK EQGYDVIAYLANIGQKEDFEEARKK ALKLGAKKVFIEDVSKEFVEEFIWP AVQSSALYEDRYLLGTSLARPCIAR RQVEIAQREGAKYVSHGATGKGNDQ VRFELTCYSLAPQIKVIAPWRMPEF YNRFKGRNDLMEYAKQHGIPIPVTP KSPWSMDENLMHISYEAGILENPKN QAPPGLYTKTQDPAKAPNSPDVLEI EFKKGVPVKVTNIKDGTTRTTSLEL FMYLNEVAGKHGVGRIDIVENRFIG MKSRGIYETPAGTILYHAHLDIEAF TMDREVRKIKQGLGLKFAELVYTGF WHSPECEFVRHCIQKSQERVEGKVQ VSVFKGQVYILGRESPLSLYNEELV SMNVQGDYEPIDATGFININSLRLK EYHRLQSKVTAK
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Gene Information

• Gene Name: Ass1 argininosuccinate synthetase 1 [ Mus musculus ]
• Official Symbol: Ass1
• Synonyms: ASS1; argininosuccinate synthetase 1; argininosuccinate synthase; arginosuccinate synthetase 1; citrulline--aspartate ligase; ASS; fold; Ass-1; AA408052; MGC103151
• Gene ID: 11898
• mRNA Refseq: NM_007494
• Protein Refseq: NP_031520

Reviews

09/04/2020

Critical expertise in protein engineering, a trusted research resource.

10/01/2019

Dependable peptide synthesis, accelerates our peptide-based projects effectively.

08/10/2018

Efficient protein purification, cost-effective and dependable.

Q&As

What are the mechanisms by which ASS1 modulates cell growth and proliferation?

ASS1 regulates cell growth by controlling the availability of arginine, a key amino acid for cell proliferation.

How does ASS1 deficiency contribute to the development of urea cycle disorders and hyperammonemia?

ASS1 deficiency leads to urea cycle disorders, causing hyperammonemia and metabolic imbalances.

What is the impact of ASS1 on amino acid metabolism and overall cellular function?

ASS1 affects amino acid metabolism, playing a critical role in cellular health and function.

How does ASS1 (Argininosuccinate Synthase 1) function in the urea cycle and nitrogen metabolism?

ASS1 is essential in the urea cycle, converting nitrogen waste into urea for excretion and maintaining nitrogen balance.

How do alterations in ASS1 expression or activity affect cardiovascular health and disease?

Variations in ASS1 activity can impact cardiovascular health, influencing nitric oxide production and vascular function.

What role does ASS1 play in the synthesis of arginine and its impact on nitric oxide production?

ASS1 is involved in arginine synthesis, impacting nitric oxide levels and vascular function.

How does ASS1 influence the response to high-protein diets or dietary restrictions in metabolic health?

ASS1 influences how the body metabolizes high-protein diets, affecting metabolic responses and health.