Recombinant Mouse ATP9A Protein, His (Fc)-Avi-tagged

• Cat.No.: ATP9A-890M
• Product Overview: Recombinant Mouse ATP9A with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Mouse
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Atp9a ATPase, class II, type 9A [ Mus musculus ]
• Official Symbol: ATP9A
• Gene ID: 11981
• mRNA Refseq: NM_015731.3
• Protein Refseq: NP_056546.2
• UniProt ID: O70228

Reviews

10/08/2022

The stability of ATP9A is very stable under a variety of environmental conditions, whether it is low temperature, high temperature, or other extreme environments, and its performance remains consistent.

06/01/2021

As the production process of ATP9A adopts the most advanced biotechnology, the production process is more green and sustainable.

11/27/2019

Due to the short half-life and high clearance rate of recombinant proteins, their rapid clearance from the body reduces the risk of side effects.

Q&As

What is the expression pattern of ATP9A gene?

ATP9A gene is widely expressed in various human tissues. However, its expression levels may vary in different tissues and cell types.

How to detect ATP9A gene mutation?

Detection of ATP9A gene mutations is usually performed by gene sequencing technology. Common methods include Sanger sequencing, next generation sequencing (NGS), etc. These methods can detect point mutations, insertion/deletion mutations and so on on ATP9A gene.

Does ATP9A gene mutation affect cell membrane stability?

The protein is involved in the phospholipid turnover process of cell membrane and maintains the stability of cell membrane. ATP9A gene mutation may lead to abnormal protein function, and then affect the stability of cell membrane.

What is the effect of ATP9A gene mutation on treatment?

Currently, there is no specific therapy targeting ATP9A gene mutations. However, understanding the mutation status of ATP9A gene can help doctors better understand the disease risk and prognosis of patients to develop individualized treatment plans.

How do ATP9A gene mutations affect the function of ATP9A protein?

This gene mutation may lead to the structural and functional abnormalities of ATP9A protein, affecting the phospholipid turnover process of the inner and outer membranes of cells. This may negatively affect the function and stability of the cells.

How do ATP9A mutations affect nervous system development?

The effects of specific ATP9A gene mutations on nervous system development are unknown. However, several studies have shown that ATP9A protein plays an important role in nerve cells, and mutations may be associated with intellectual disability and neurodevelopmental abnormalities.