Recombinant Mouse ATRX Protein, His (Fc)-Avi-tagged

• Cat.No.: ATRX-898M
• Product Overview: Recombinant Mouse ATRX with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Mouse
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Atrx alpha thalassemia/mental retardation syndrome X-linked homolog (human) [ Mus musculus ]
• Official Symbol: ATRX
• Gene ID: 22589
• mRNA Refseq: NM_009530.2
• Protein Refseq: NP_033556.2
• UniProt ID: Q61687

Reviews

10/20/2022

The purity of ATRX is very high, which can ensure the reliability of the experimental results and also facilitate the subsequent experimental operation.

10/26/2019

ATRX is really amazing. The results of every experiment are very consistent, which shows that its production process is very careful.

07/24/2019

This band positions of ATRX in Western blot were accurate and showed good specificity.

Q&As

What progress has been made in the research of ATRX gene?

The research on ATRX gene mainly focuses on its function and regulatory mechanism, and its relationship with genetic diseases and cancer. So far, several important findings on ATRX gene function and regulation have been made.

Is ATRX gene regulated?

Yes, ATRX gene expression is affected by a variety of regulatory factors, including transcription factor binding, DNA methylation status, etc. These regulatory mechanisms ensure the adaptability and stability of the ATRX gene.

What diseases or symptoms are caused by ATRX mutation?

ATRX gene mutation can lead to Alpha thalassemia/mental retardation syndrome X-linked. The main features of this syndrome include mental retardation, developmental delay, craniofacial deformity, anemia, etc.

What is the expression pattern of ATRX gene?

ATRX gene is widely expressed in human body, but its expression level may vary in different tissues and organs. Its expression is higher in brain, kidney, muscle and other tissues.

Are there other genes that interact with the ATRX gene?

ATRX genes may interact with other genes related to chromatin structure and DNA repair. For example, ATRX interacts with Death-domain associated protein (DAXX) to participate in chromatin repair and regulation.

Is ATRX gene involved in DNA repair?

Yes, the ATRX gene is involved in the regulation of DNA repair. Together with other proteins, it maintains the normal progression of DNA repair by maintaining chromatin structure and regulating gene expression.