Recombinant Mouse Bmpr1b protein(Lys14-Lys126), hFc-tagged

• Cat.No.: Bmpr1b-820M
• Product Overview: Recombinant Mouse Bmpr1b (NP_031586.1) (Lys14-Lys126) was expressed in HEK293 with the Fc region of Human IgG1 at the C-terminus.

Specification

• Source: HEK293
• Species: Mouse
• Tag: C-hFc
• Protein length: Lys14-Lys126
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Bio-activity: Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells. The ED50 for this effect is 1.5-7.5 μg/mL.
• Molecular Mass: The recombinant mouse Bmpr1b consists 351 amino acids and predicts a molecular mass of 39.4 kDa.
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Bmpr1b bone morphogenetic protein receptor, type 1B [ Mus musculus ]
• Official Symbol: Bmpr1b
• Synonyms: BMPR1B; bone morphogenetic protein receptor, type 1B; bone morphogenetic protein receptor type-1B; BMP type-1B receptor; activin receptor-like kinase 6; serine/threonine-protein kinase receptor R6; Alk6; SKR6; ALK-6; Acvrlk6; BMPR-1B; BMPR-IB; CFK-43a; AI385617; AV355320
• Gene ID: 12167
• mRNA Refseq: NM_007560
• Protein Refseq: NP_031586

Reviews

07/24/2021

Great performance in ELISA.

02/02/2018

Researchers can confidently rely on this high-quality protein to produce accurate and reproducible results, thereby accelerating their research progress

08/15/2017

Its well-established reputation and reliability further contribute to its suitability for a wide range of experimental designs.

Q&As

Can BMPR1B be targeted for regenerative medicine purposes?

Yes, the role of BMPR1B in tissue regeneration, especially in bone and cartilage, makes it a potential target for regenerative medicine approaches.

In what ways can BMPR1B be targeted for therapeutic purposes?

Therapeutic strategies may involve the use of small molecules, antibodies, or gene therapies to modulate BMPR1B activity for treating various clinical conditions.

How does BMPR1B protein contribute to fertility in humans?

BMPR1B is involved in the regulation of ovarian function and follicular development, making it relevant to fertility treatments and reproductive medicine.

How does BMPR1B contribute to the development of the nervous system?

BMPR1B is involved in neural development, and understanding its role could have implications for neuroregenerative medicine and the treatment of neurodevelopmental disorders.

Is BMPR1B associated with any autoimmune diseases?

While the direct association with autoimmune diseases is not well-established, the role of BMPR1B in immune regulation might be explored for potential implications in autoimmune disorders.