Recombinant Mouse Btc Protein (Asp32-Gln118), N-His tagged

• Cat.No.: Btc-5414M
• Product Overview: Recombinant mouse Btc (Asp32-Gln118) fused with the N-terminal His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the epidermal growth factor (EGF) family. These growth factors are ligands for the EGFR/ErbB receptor tyrosine kinases, and play roles in cell growth and differentiation. The encoded protein is synthesized as a transmembrane precursor that is proteolytically cleaved to generate a mature peptide, and plays a role in the differentiation of pancreatic beta cells. This gene may also play a protective role in acute pancreatitis, whereas increased expression of this gene may contribute to diabetic macular edema. Gene therapy using combinations of this gene and other pancreas-specific transcription factors may induce islet neogenesis and remediate hyperglycemia in type 1 diabetes.
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 9.57 kDa
• Protein Length: Asp32-Gln118
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Btc betacellulin, epidermal growth factor family member [ Mus musculus (house mouse) ]
• Official Symbol: Btc
• Synonyms: Btc; betacellulin, epidermal growth factor family member; Bcn; betacellulin; probetacellulin
• Gene ID: 12223
• mRNA Refseq: NM_007568
• Protein Refseq: NP_031594
• UniProt ID: Q05928