Recombinant Mouse Cd34 protein(Met1-Thr287), His-tagged

• Cat.No.: Cd34-3313M
• Product Overview: Recombinant Mouse Cd34 protein(NP_001104529.1)(Met1-Thr287), fused with C-terminal His tag, was expressed in HEK293.

Specification

• similar: Cd34
• Alias: CD34; CD34 antigen; hematopoietic progenitor cell antigen CD34; cluster designation 34; AU040960
• Source: HEK293
• Species: Mouse
• Conjugate: C-His
• Tag: C-His
• Protein length: Met1-Thr287
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• MolecularMass: The recombinant mouse CD34 consists of 264 amino acids and has a predicted molecular mass of 28.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCD34 is approximately 50-60 kDa due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 98 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• GeneName: Cd34 CD34 antigen [ Mus musculus ]
• GeneNameWeblink: 12490
• OfficialSymbol: Cd34
• OfficialSymbolWeblink: 12490
• GeneID: 12490
• GeneIDWeblink: 12490
• mRNARefseq: NM_001111059
• mRNARefseqWeblink: NM_001111059.1
• ProteinRefseqWeblink: NP_001104529.1
• Synonyms: CD34; CD34 antigen; hematopoietic progenitor cell antigen CD34; cluster designation 34; AU040960

Gene Information

• Synonyms: CD34; CD34 antigen; hematopoietic progenitor cell antigen CD34; cluster designation 34; AU040960

Reviews

07/02/2022

CD34 protein may have a specific binding affinity or interaction with its target molecules or receptors, making it a valuable tool for targeted therapies or diagnostic applications.

04/06/2019

In some cases, manufacturers may be open to collaborating with researchers to further investigate the applications and potential of CD34 protein.

03/03/2018

If researchers require modifications or specific variants of CD34 protein for their experiments, the manufacturer could potentially offer custom protein engineering services to meet their needs.

01/30/2016

This collaboration can involve sharing resources, expertise, and data to advance scientific understanding and therapeutic development.

Q&As

How is CD34 used in the assessment of bone marrow health?

CD34 is employed as a marker to evaluate the status of bone marrow, aiding in the diagnosis and monitoring of disorders affecting the bone marrow.

How does CD34 impact the prognosis of hematologic diseases?

CD34 expression levels are sometimes correlated with the prognosis of certain hematologic diseases, helping clinicians predict disease outcomes and plan appropriate interventions.

How does CD34 contribute to the understanding of hematologic malignancies?

CD34 expression patterns are studied to gain insights into the pathogenesis and progression of hematologic malignancies, aiding in the development of targeted therapies.

Can CD34 be used to monitor the effectiveness of cancer treatments?

Yes, changes in CD34 expression can be indicative of the response to cancer treatments, providing valuable information for patient management.

Are there any specific therapeutic applications of CD34?

CD34 is a target for therapeutic interventions, and research is ongoing to explore its potential for developing treatments for various diseases.

Is CD34 exclusively used in hematological research, or does it have applications in other medical fields?

While CD34 is prominently used in hematological research, its role in angiogenesis extends its applications to cardiovascular research and regenerative medicine.