Description : |
Predicted to enable several functions, including SH3 domain binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in nervous system development and positive regulation of cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell activation; positive regulation of cytokine production; and regulation of signal transduction. Located in several cellular components, including dendritic spine; external side of plasma membrane; and immunological synapse. Part of alpha-beta T cell receptor complex. Is expressed in colon and hemolymphoid system. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3E (CD3e molecule). |
Source : |
HEK293 |
Species : |
Mouse |
Tag : |
Fc |
Form : |
Lyophilized |
Molecular Mass : |
36 kDa |
Protein Length : |
189 |
AA Sequence : |
MRWNTFWGILCLSLLAVGTCQDDAE NIEYKVSISGTSVELTCPLDSDENL KWEKNGQELPQKHDKHLVLQDFSEV EDSGYYVCYTPASNKNTYLYLKARV CEYCVEVDLTAVAIIIIVDICITLG LLMVIYYWSKNRKAKAKPVTRGTGA GSRPRGQNKERPPPVPNPDYEPIRK GQRDLYSGLNQRAV |
Purity : |
> 98% |
Applications : |
WB; ELISA; FACS; FC |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
At -20 centigrade. |
Concentration : |
1 mg/mL |
Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |