Recombinant Mouse Cd55 Protein, His-tagged

• Cat.No.: Cd55-7191M
• Product Overview: Recombinant Mouse Cd55 Protein with a His tag.

Specification

• Description: This gene encodes an inhibitor of both the classical and the alternative pathways of complement activation. The encoded preproprotein undergoes post-translational processing to generate a mature polypeptide anchored to the plasma membrane via a glycosylphosphatidylinositol moiety. Erythrocytes from mice deficient in the encoded protein exhibit impaired regulation of complement activation resulting in enhanced complement deposition. Mice lacking the encoded protein exhibit enhanced susceptibility to experimentally induced myasthenia gravis. This gene is located adjacent to a closely related gene on chromosome 1.
• Species: Mouse
• Tag: His
• Form: Liquid
• Molecular Mass: 36.8 kDa
• Protein length: 35-362
• AA Sequence: DCGPPPDIPNARPILGRHSKFAEQS KVAYSCNNGFKQVPDKSNIVVCLEN GQWSSHETFCEKSCVAPERLSFASL KKEYLNMNFFPVGTIVEYECRPGFR KQPPLPGKATCLEDLVWSPVAQFCK KKSCPNPKDLDNGHINIPTGILFGS EINFSCNPGYRLVGVSSTFCSVTGN TVDWDDEFPVCTEIHCPEPPKINNG IMRGESDSYTYSQVVTYSCDKGFIL VGNASIYCTVSKSDVGQWSSPPPRC IEKSKVPTKKPTINVPSTGTPSTPQ KPTTESVPNPGDQPTPQKPSTVKVS ATQHVPVTKTTVRHPIRTSTDKGEP NTGLEHHHHHH
• Endotoxin: < 1.0 EU/μg of protein (determined by LAL method)
• Purity: > 95 % by SDS-PAGE
• Stability: Shelf life: one year from despatch.
• Storage: Store undiluted at 2-8 centigrade for one week or (in aliquots) at -20 to -80 centigrade for longer. Avoid repeated freezing and thawing.
• Concentration: 0.5 mg/mL (determined by absorbance at 280nm)
• Storage Buffer: Phosphate Buffered Saline (pH 7.4) containing 10 % glycerol.

Gene Information

• Gene Name: Cd55 CD55 molecule, decay accelerating factor for complement [ Mus musculus (house mouse) ]
• Official Symbol: Cd55
• Synonyms: Cd55; CD55 molecule, decay accelerating factor for complement; Daf; Daf-; Daf1; GPI-; Daf-GPI; GPI-DAF; complement decay-accelerating factor, GPI-anchored; CD55 antigen; Cromer blood group; GPI anchor addition signal; complement-glycosylphosphatidylinositol; decay accelerating factor 1
• Gene ID: 13136
• mRNA Refseq: NM_010016
• Protein Refseq: NP_034146
• UniProt ID: Q61475