Description : |
This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein die in utero due to vascular insufficiency, caused by increased endothelial apoptosis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. |
Source : |
Insect cell |
Species : |
Mouse |
Tag : |
His |
Form : |
Liquid |
Molecular Mass : |
66.2 kDa |
Protein length : |
25-599 |
AA Sequence : |
GPNFPQIDTPNMLPAHHRQKRDWIW NQMHIDEEKNESLPHYVGKIKSNVN RQNAKYVLQGEFAGKIFGVDANTGN VLAYERLDREKVSEYFLTALIVDKN TNKNLEQPSSFTVKVHDINDNWPVF SHQVFNASVPEMSAIGTSVIRVTAV DADDPTVAGHATVLYQIVKGNEYFS IDNSGLIFTKIKNLDREKQAEYKIV VETQDALGLRGESGTATVMIRLEDI NDNFPVFTQSTYTFSVPEDIRVGKP LGFLTVVDPDEPQNRMTKYSIMQGE YRDTFTIETDPKRNEGIIKPTKSLD YEVIQQYTFYIEATDPTIRYEYLSS TSGKNKAMVTINVLDVDEPPVFQRH FYHFKLPENQKKPLIGTVVAKDPDK AQRSIGYSIRKTSDRGQFFRITKQG NIYNEKELDRETYAWYNLTVEANEL DSRGNPVGKESIVQVYIEVLDENDN PPEFAQPYEPKVCENAAQGKLVVQI SATDKDVVPVNPKFKFALKNEDSNF TLINNHDNTANITVKYGQFNREHAK FHYLPVLISDNGVPSLTGTSTLTVG VCKCNEQGEFTFCEEMAAQAGVSIQ LEHHHHHH |
Endotoxin : |
< 1.0 EU/μg of protein (determined by LAL method) |
Purity : |
> 90 % by SDS-PAGE |
Stability : |
Shelf life: one year from despatch. |
Storage : |
Store undiluted at 2-8 centigrade for one week or (in aliquots) at -20 to -80 centigrade for longer. Avoid repeated freezing and thawing. |
Concentration : |
0.5 mg/mL (determined by absorbance at 280nm) |
Storage Buffer : |
Phosphate Buffered Saline (pH 7.4) containing 10 % glycerol. |