Recombinant Mouse Clu protein, His-tagged

• Cat.No.: Clu-5774M
• Product Overview: Recombinant Mouse Clu aa. (Ser227~Glu447 (Accession # Q06890)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a secreted chaperone that can, under some stress conditions, also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. The encoded preproprotein undergoes proteolytic processing to generate a disulfide-linked heterodimeric mature protein comprised of alpha and beta subunits. Mice lacking the encoded protein exhibit increased severity of autoimmune myocarditis, faster progression of the acute inflammation to myocardial scarring and decreased brain injury following neonatal hypoxic-ischemic injury.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 27 kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Ser227~Glu447 (Accession # Q06890)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Clu clusterin [ Mus musculus (house mouse) ]
• Official Symbol: Clu
• Synonyms: Cli; ApoJ; Sgp2; SP-40; Sgp-2; Sugp-2; AI893575; D14Ucla3; Apolipoprotein J; clustrin; complement lysis inhibitor; sulfated glycoprotein 2; testosterone repressed prostate message; testosterone repressed prostate message-2; clusterin
• Gene ID: 12759
• mRNA Refseq: NM_013492.3
• Protein Refseq: NP_038520.2
• UniProt ID: Q06890