Recombinant Mouse COL18A1 Protein

• Cat.No.: COL18A1-3722M
• Product Overview: Recombinant Mouse COL18A1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Col18a1 collagen, type XVIII, alpha 1 [ Mus musculus ]
• Official Symbol: COL18A1
• Gene ID: 12822
• mRNA Refseq: NM_001109991.1
• Protein Refseq: NP_001103461.1
• UniProt ID: P39061

Reviews

06/01/2022

The delivery was well-coordinated and timely.

09/12/2019

Superior quality resonates in this lab product, supported by customer service that is genuinely helpful.

12/23/2018

The lab product showcases commendable quality.

Q&As

Can you discuss the role of COL18A1 in neurobiology, particularly its involvement in the central nervous system and potential implications for neurodegenerative disorders?

COL18A1 has roles in the central nervous system. Understanding its functions provides insights into potential implications for neurodegenerative disorders and neural tissue development.

In angiogenesis, how does COL18A1 influence blood vessel formation, and what molecular mechanisms are involved in its regulation of endothelial cell behavior?

COL18A1 plays a role in angiogenesis by regulating endothelial cell behavior. It interacts with integrins and growth factors, influencing signaling pathways essential for blood vessel formation.

What evidence supports the involvement of COL18A1 mutations in human diseases, and how do these mutations impact COL18A1 function and tissue homeostasis?

Mutations in COL18A1 are associated with various diseases. Understanding the impact of these mutations on collagen XVIII function provides insights into their roles in tissue homeostasis and disease pathology.

How does COL18A1 contribute to the regulation of cellular senescence, and are there implications for age-related diseases and tissue degeneration?

COL18A1 has been implicated in the regulation of cellular senescence. Understanding its role in age-related diseases may provide insights into tissue degeneration and potential therapeutic targets.

In cancer progression, how does COL18A1 influence tumor behavior, metastasis, and interactions with the tumor microenvironment?

COL18A1 is implicated in cancer progression, affecting tumor behavior and metastasis. Its interactions within the tumor microenvironment contribute to the regulation of invasive phenotypes.