Recombinant Mouse Ctsc Protein, Myc/DDK-tagged

• Cat.No.: Ctsc-2368M
• Product Overview: Purified recombinant protein of mouse full-length cathepsin C (Ctsc), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the dipeptidyl peptidase 1 light, heavy, and exclusion domain chains, which together comprise one subunit of the homotetrameric enzyme. This enzyme has amino dipeptidase activity and may play a role in the activation of granzymes during inflammation. Homozygous knockout mice for this gene exhibit impaired granzyme activation and enhanced survival in a sepsis model.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 52.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ctsc cathepsin C [ Mus musculus (house mouse) ]
• Official Symbol: Ctsc
• Synonyms: CTSC; cathepsin C; dipeptidyl peptidase 1; DPP-I; cathepsin J; dipeptidylpeptidase 1; dipeptidyl peptidase I; dipeptidyl transferase; dipeptidyl-peptidase 1; dipeptidyl-peptidase I; DPP1; DPPI; AI047818
• Gene ID: 13032
• mRNA Refseq: NM_009982
• Protein Refseq: NP_034112
• UniProt ID: P97821