Recombinant Mouse Cyp2w1 Protein, Myc/DDK-tagged
Cat.No. : | Cyp2w1-2420M |
Product Overview : | Purified recombinant protein of mouse full-length cytochrome P450, family 2, subfamily w, polypeptide 1 (Cyp2w1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | A cytochrome P450 monooxygenase that may play a role in retinoid and phospholipid metabolism. Catalyzes the hydroxylation of saturated carbon hydrogen bonds. Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may regulate atRA clearance. Other retinoids such as all-trans retinol and all-trans retinal are potential endogenous substrates. Catalyzes both epoxidation of double bonds and hydroxylation of carbon hydrogen bonds of the fatty acyl chain of 1-acylphospholipids/2-lysophospholipids. Can metabolize various lysophospholipids classes including lysophosphatidylcholines (LPCs), lysophosphatidylinositols (LPIs), lysophosphatidylserines (LPSs), lysophosphatidylglycerols (LPGs), lysophosphatidylethanolamines (LPEs) and lysophosphatidic acids (LPAs). Has low or no activity toward 2-acylphospholipids/1-lysophospholipids, diacylphospholipids and free fatty acids. May play a role in tumorigenesis by activating procarcinogens such as aflatoxin B1, polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 54.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Cyp2w1 |
Synonyms : | CYP2W1; cytochrome P450, family 2, subfamily w, polypeptide 1; Gm455 |
Gene ID : | 545817 |
mRNA Refseq : | NM_001160265 |
Protein Refseq : | NP_001153737 |
UniProt ID : | E9Q816 |
Products Types
◆ Recombinant Protein | ||
CYP2W1-2152M | Recombinant Mouse CYP2W1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP2W1-705H | Recombinant Human CYP2W1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYP2W1-2271H | Recombinant Human CYP2W1 Protein, GST-tagged | +Inquiry |
CYP2W1-4204M | Recombinant Mouse CYP2W1 Protein | +Inquiry |
◆ Lysates | ||
CYP2W1-7107HCL | Recombinant Human CYP2W1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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