Recombinant Mouse Dcp1a Protein, Myc/DDK-tagged

• Cat.No.: Dcp1a-2476M
• Product Overview: Purified recombinant protein of mouse full-length decapping mRNA 1A (Dcp1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 65.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dcp1a decapping mRNA 1A [ Mus musculus (house mouse) ]
• Official Symbol: Dcp1a
• Synonyms: DCP1A; DCP1 decapping enzyme homolog A (S. cerevisiae); mRNA-decapping enzyme 1A; decapping enzyme; transcription factor SMIF; Smad4-interacting transcriptional co-activator; MAD homolog 4 interacting transcription coactivator 1; MAD homolog 4-interacting transcription coactivator 1; SMIF; Mitc1; AU019772; D14Ertd817e; 1110066A22Rik; 4930568L04Rik
• Gene ID: 75901
• mRNA Refseq: NM_133761
• Protein Refseq: NP_598522
• UniProt ID: Q91YD3